Apigenin inhibits COX-2, PGE2, and EP1 and also initiates terminal differentiation in the epidermis of tumor bearing mice.

Faculty	Pharmacy	Year:	2016
Type of Publication:	ZU Hosted	Pages:
Authors:	Eman Salah Abdelaziz Souliman Staff Zu Site Abstract In Staff Site
Journal:	Prostaglandins Leukot Essent Fatty Acids Elsevier	Volume:

Keywords :	Apigenin inhibits COX-2, PGE2, , , , also initiates
Abstract:	Non-melanoma skin cancer (NMSC) is the most prevalent cancer in the United States. NMSC overexpresses cyclooxygenase-2 (COX-2). COX-2 synthesizes prostaglandins such as PGE2 which promote proliferation and tumorigenesis by engaging G-protei

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