Central GPR109A Activation Mediates Glutamate-Dependent Pressor Response in Conscious Rats.

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Samar Abdelmigeed Mohamed Rezk
Journal: J Pharmacol Exp Ther. USA Volume:
Keywords : Central GPR109A Activation Mediates Glutamate-Dependent Pressor    
Abstract:
G protein-coupled receptor 109A (GPR109A) activation by its ligand nicotinic acid (NA) in immune cells increases Ca(2+) levels, and Ca(2+) induces glutamate release and oxidative stress in central blood pressure (BP)-regulating nuclei, for
   
     
 
       

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