Synthesis of Some New Pyrimidine Derivatives of Expected Antimicrobial Activity

Faculty Science Year: 2008
Type of Publication: ZU Hosted Pages:
Authors:
weSam Saber Mohammed Shehab
Journal: Phosphorus, Sulfur, and Silicon, 183:115–135, 2008 Phosphorus, Sulfur, and Silicon, 183:115–135, 2008 Volume:
Keywords : Synthesis , Some , Pyrimidine Derivatives of Expected Antimicrobial    
Abstract:
2-(2-Arylvinyl)-6-methyl-4-mercapto-5-acetylpyrimidine derivatives 3a−d, were synthesized form the reaction of the appropriate isothiocyanate derivatives 1 with α,β-unsaturated aminoketone 2. Compound 3 was alkylated with methyl iodide,
   
     
 
       

Author Related Publications

  • weSam Saber Mohammed Shehab, "Novel saccharin analogs as promising antibacterial and anticancer agents: synthesis, DFT, POM analysis, molecular docking, molecular dynamic simulations, and cell-based assay", Frontiers, 2022 More
  • weSam Saber Mohammed Shehab, "Synthesis,Characterization and Evaluation of the Anticancer and Antimicrobial Activities of Some Novel Benzazole and Benzazine Derivatives", Council for Innovative Research, 2013 More
  • weSam Saber Mohammed Shehab, "Synthesis and Electrochemical Behavior of Some New Pyridazine Derivatives", International Journal of Basic and Applied Sciences, 1 (3) (2012) 202-218, 2012 More
  • weSam Saber Mohammed Shehab, "Synthesis of some new S‐glycosyl pyrimidine and condensed pyrimidine derivatives", European Journal of Chemistry, 2012 More
  • weSam Saber Mohammed Shehab, "Nanoparticles of manganese oxides as efficient catalyst for the synthesis of pyrano[2,3‑d]pyrimidine derivatives and their complexes as potent protease inhibitors", Journal of the Iranian Chemical Society, 2018 More

Department Related Publications

  • Wael Salah AbdelHalim, "Tuning hydrogen storage of carbon nanotubes by mechanical bending: theoretical study", Taylor and Francis, 2016 More
  • Amira Atef Mahmoud Ghoneim, "Utilization of Multi Component Reactions in the Synthesis of 1,6- Naphthyridine Derivatives with Expected Biological Activity", National Information and Documentation Center (NIDOC), 2024 More
  • weSam Saber Mohammed Shehab, "Synthesis, molecular docking, assessment of biological and anti-diabetic properties of benzalacetophenone derivatives", Nature Publishing Group UK, 2025 More
Tweet