Synthesis of new acridines and hydrazones derived from cyclic β-diketone for cytotoxic and antiviral evaluation

Faculty Pharmacy Year: 2009
Type of Publication: ZU Hosted Pages: (2009) 3680–3686
Authors:
Osama Ibrahim Abdou Elsabagh
Journal: European Journal of Medicinal Chemistry http://www.elsevier.com/locate/ejmech Volume:
Keywords : Synthesis , , acridines , hydrazones derived from cyclic    
Abstract:
Cyclic b-diketone namely, dimedone was utilized to prepare different chemical entities whether cyclic such as acridines, thiadiazole and triazole or acyclic systems as hydrazide, hydrazones, thiosemicarbazide and semicarbazide. The struct
    
     
 
       

Author Related Publications

  • Osama Ibrahim Abdou Elsabagh, "Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors", Taylor & Francis Group, 2022 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis of Some New Benzisothiazolone and Benzenesulfonamide Derivatives of Biological Interest Starting from Saccharin Sodium", 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2013 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis and Biological Evaluation of Some N-Arylpyrazoles and Pyrazolo[3,4-d]pyridazines as Anti-Inflammatory Agents", 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2013 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity", springer, 2012 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis and pharmacological studies for some new benzotriazole and dibenzodiazepine derivatives as antipsychotic agents", KOREAN CHEMICAL SOC, 2009 More

Department Related Publications

  • Mahmoud Mohamed Mohamed Sebaee, "Rapid RP-HPLC Method for Simultaneous Estimation of Some Antidiabetics; Metformin, Gliclazide and Glimepiride in Tablets", ejchem.journals.ekb.eg, 2018 More
  • Rania Hamdy Ahmed Badawi, "Design, synthesis, and computational validation of novel compounds selectively targeting HER2-expressing breast cancer", Elsevier, 2020 More
  • Mahmoud Mohamed Mohamed Sebaee, "Toxicity Profile and Pharmacokinetic Study of Antibiotic Mixtures, Gentamicin and Vancomycin, in Rat Plasma by Ecofriendly Liquid Chromatography Coupled Tandem Mass Spectrometry", acs publications, 2020 More
  • Mohammed Mohamed Mahmoud Baraka, "Toxicity Profile and Pharmacokinetic Study of Antibiotic Mixtures, Gentamicin and Vancomycin, in Rat Plasma by Ecofriendly Liquid Chromatography Coupled Tandem Mass Spectrometry", acs publications, 2020 More
  • Sobhi Mohamed Mahmoud Ibrahym, "Toxicity Profile and Pharmacokinetic Study of Antibiotic Mixtures, Gentamicin and Vancomycin, in Rat Plasma by Ecofriendly Liquid Chromatography Coupled Tandem Mass Spectrometry", acs publications, 2020 More
Tweet