Correlations between P53 mutations and response to Paclitaxel/Cisplatin Chemotherapy in Patients with Advanced Epithelial Ovarian Cancer

Faculty Medicine Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Journal of American Science marsland press Volume: 11
Keywords : Correlations between , mutations , response , Paclitaxel/Cisplatin Chemotherapy    
Abstract:
The p53 gene plays an important role in cellular response to DNA damage and has been implicated in the response to platinum compounds in patients with ovarian carcinoma. Because taxanes could induce p53-independent apoptosis, we studied t
   
     
 
       

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