Click reaction based synthesis, antimicrobial, and cytotoxic activities of new 1,2,3-triazoles

Faculty Science Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Hossam Aly Hussein Saad
Journal: Bioorganic & Medicinal Chemistry Letters Elsevier Ltd. Volume:
Keywords : Click reaction based synthesis, antimicrobial, , cytotoxic    
Abstract:
Three-motif pharmacophoric models 20a–e and 21–25 were prepared in good yields by CuAAC of two azido substrates 2 and 11 with seven terminal acetylenic derivatives including chalcones 17a–e, theo- phylline 18 and cholesterol 19. The structu
    
     
 
       

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  • Hossam Aly Hussein Saad, "Spectrophotometric and thermodynamic studies on the 1:1 charge transfer interaction of several clinically important drugs with tetracyanoethylene in solution-state: Part one", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "Charge-Transfer Complexes of Two Highly Efficient Drugs with σ- and π-Acceptors: Spectroscopic, Thermal, and Surface Morphology Characteristics", Springer, 2016 More

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