Click reaction based synthesis, antimicrobial, and cytotoxic activities of new 1,2,3-triazoles

Faculty Science Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Hossam Aly Hussein Saad
Journal: Bioorganic & Medicinal Chemistry Letters Elsevier Ltd. Volume:
Keywords : Click reaction based synthesis, antimicrobial, , cytotoxic    
Abstract:
Three-motif pharmacophoric models 20a–e and 21–25 were prepared in good yields by CuAAC of two azido substrates 2 and 11 with seven terminal acetylenic derivatives including chalcones 17a–e, theo- phylline 18 and cholesterol 19. The structu
    
     
 
       

Author Related Publications

  • Hossam Aly Hussein Saad, "Charge transfer interaction of organic p-acceptors with the anti-hyperuricemic drug allopurinol: Insights from IR, Raman, 1H NMR and 13C NMR spectroscopies", Publisher: Croatian Pharmaceutical Society,, 2016 More
  • Hossam Aly Hussein Saad, "Charge transfer complexation of the anticholinergic drug clidinium bromide and picric acid in different polar solvents: Solvent effect on the spectroscopic and structural morphology properties of the product", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "THIOSEMICARBAZIDES, POTENT REAGENTS FOR SYNTHESIS OF SOME NEW 1,4-DIPHENYLBENZO[g]QUINOXALINE-5,10-DIONE BASED HETEROCYCLES", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "Spectrophotometric and thermodynamic studies on the 1:1 charge transfer interaction of several clinically important drugs with tetracyanoethylene in solution-state: Part one", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "Charge-Transfer Complexes of Two Highly Efficient Drugs with σ- and π-Acceptors: Spectroscopic, Thermal, and Surface Morphology Characteristics", Springer, 2016 More

Department Related Publications

  • Wael Abdullah Metwally Zordq, "Synthesis, thermal analyses, characterization and biological evaluation of new enrofloxacin vanadium(V) solvates(L) (L ¼ An, DMF, Py, Et3N and o-Tol)", usa, 2016 More
  • Sedik Attia Sedik Mohammed, "Synthesis, thermal analyses, characterization and biological evaluation of new enrofloxacin vanadium(V) solvates(L) (L ¼ An, DMF, Py, Et3N and o-Tol)", usa, 2016 More
  • Hamada Mohamed Ahmed Kaila , "effect of some Azo compound and chlorid ions in the kinetic corrosion parameters of copper in H2SO4 solution", america, 1991 More
  • Walaa Helmy Fahmy Sheweny, "Synthesis of Pd(II), Ag(I), Pt(IV), and Hg(II) Complexes with Nifuroxazide, Their Structure, DFT Modeling, and Antimicrobial and Anticancer Activity1", springer, 2018 More
  • Walaa Helmy Fahmy Sheweny, "Synthesis and cytotoxic evaluation of some substituted pyrazole zirconium (IV) complexes and their biological assay", wiely, 2018 More
Tweet