Synthesis and biological screening of new derivatives of 2,3-dihydro quinazolin-4(1H)-one and benzotriazepin- 5(2H)-one for central nervous system activity

Faculty Pharmacy Year: 2014
Type of Publication: ZU Hosted Pages:
Authors:
Mansour Alsayed Mansour Abokol
Journal: International Journal of Pharmaceutical Chemistry International Volume:
Keywords : Synthesis , biological screening , , derivatives , 2,3-dihydro quinazolin-4(1H)-one    
Abstract:
A new syntheses of novel series of 2,3-dihydroquinazolin-4(1H)-one and benzotriazepin- 5(2H)-one derivatives, starting from the same intermediate (IIa-g). By varying the substituent on the benzamide moiety of the key intermediate (IIa-g) or
    
     
 
       

Author Related Publications

  • Mansour Alsayed Mansour Abokol, "Synthesis of certain Arylalkanoic Acid Derivatives of pharmacutical Interest", لايوجد, 1900 More
  • Mansour Alsayed Mansour Abokol, "Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides", ELSEVIER, 2013 More
  • Mansour Alsayed Mansour Abokol, "SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN- 4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS.", International, 2013 More
  • Mansour Alsayed Mansour Abokol, "DESIGN AND SYNTHESIS OF N4, N9- DISUBSTITUTED SPERMINES FOR NON-VIRAL SIRNA DELIVERY – STRUCTURE – ACTIVITY RELATIONSHIP STUDIES OF SIFECTION EFFICIENCY VERSUS TOXICITY", Pharmaceutical Research, Vol. 26, No. 2, February (2009), 2009 More
  • Mansour Alsayed Mansour Abokol, "DESIGN AND SYNTHESIS AND IN VITRO ANTICANCER EVALUATION OF 4,6-DIAMINO 1,3,5-TRIAZINE-2-CARBOHYDRAZIDES AND CARBOXAMIDES", Med. Chem. Lett. 23, 2013 More

Department Related Publications

  • Mansour Alsayed Mansour Abokol, "Synthesis of certain Arylalkanoic Acid Derivatives of pharmacutical Interest", لايوجد, 1900 More
  • Mahmoud Mohamed Mohamed Sebaee, "Potential Role of Sulfur Nanoparticles as Antitumor and Antioxidant in Mice", Scholars Research Library, 2018 More
  • Kamel Abdelrehem Metwaly Bayomy, "Pyrimido[4,5-c]quinolin-1(2H)-ones as a novel class of antimitotic agents: synthesis and in vitro cytotoxic activity", Elsevier, 2007 More
  • Alsayed Mohamed Mansour Lashen , "Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents", Elsevier, 2016 More
  • Samar Saied Mahmoud Mohamed Elbaramawy, "Design, synthesis, in vitro and in silico evaluation of novel substituted 1,2,4-triazole analogues as dual human VEGFR-2 and TB-InhA inhibitors", ELSEVIER, 2023 More
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