Synthesis and biological screening of new derivatives of 2,3-dihydro quinazolin-4(1H)-one and benzotriazepin- 5(2H)-one for central nervous system activity

Faculty Pharmacy Year: 2014
Type of Publication: ZU Hosted Pages:
Authors:
Mansour Alsayed Mansour Abokol
Journal: International Journal of Pharmaceutical Chemistry International Volume:
Keywords : Synthesis , biological screening , , derivatives , 2,3-dihydro quinazolin-4(1H)-one    
Abstract:
A new syntheses of novel series of 2,3-dihydroquinazolin-4(1H)-one and benzotriazepin- 5(2H)-one derivatives, starting from the same intermediate (IIa-g). By varying the substituent on the benzamide moiety of the key intermediate (IIa-g) or
    
     
 
       

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  • Mansour Alsayed Mansour Abokol, "Synthesis of certain Arylalkanoic Acid Derivatives of pharmacutical Interest", لايوجد, 1900 More
  • Mansour Alsayed Mansour Abokol, "Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides", ELSEVIER, 2013 More
  • Mansour Alsayed Mansour Abokol, "SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN- 4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS.", International, 2013 More
  • Mansour Alsayed Mansour Abokol, "DESIGN AND SYNTHESIS OF N4, N9- DISUBSTITUTED SPERMINES FOR NON-VIRAL SIRNA DELIVERY – STRUCTURE – ACTIVITY RELATIONSHIP STUDIES OF SIFECTION EFFICIENCY VERSUS TOXICITY", Pharmaceutical Research, Vol. 26, No. 2, February (2009), 2009 More
  • Mansour Alsayed Mansour Abokol, "DESIGN AND SYNTHESIS AND IN VITRO ANTICANCER EVALUATION OF 4,6-DIAMINO 1,3,5-TRIAZINE-2-CARBOHYDRAZIDES AND CARBOXAMIDES", Med. Chem. Lett. 23, 2013 More

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  • Mansour Alsayed Mansour Abokol, "SYNTHESIS OF 3- SUBSTITUTED (6-BROMO-2-IMIDAZO {4, 5- B} PYRIDINYL) PROPIONIC ACID AS ANTIINFLAMMATORY, ANALGESIC, AND ANTIPYTRIC AGENTS", Zag. J. Pharm. Sci., Vol. 1 No. 1 Nov. Pp 129-139 June, 1993 More
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  • Sobhi Mohamed Mahmoud Ibrahym, "47. Hplc determination of three cephalosporines (cefipime, ceftriaxone , cefotaxime) in their bulk and dosage form", Asian J .Pharm. Ana., 2014 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Triple targeting of mutant EGFRL858R/T790M, COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation", Taylor and francis, 2023 More
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