Tissue-specific methylation of human insulin gene and PCR assay for monitoring Beta cell death

Faculty Pharmacy Year: 2014
Type of Publication: ZU Hosted Pages:
Authors:
Journal: PLOS ONE PLOS ONE Volume: 4
Keywords : Tissue-specific methylation , human insulin gene , , assay    
Abstract:
The onset of metabolic dysregulation in type 1 diabetes (T1D) occurs after autoimmune destruction of the majority of pancreatic insulin-producing beta cells. We previously demonstrated that the DNA encoding the insulin gene is uniquely unme
   
     
 
       

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