Synthesis and Biological Evaluation of Some N-Arylpyrazoles and Pyrazolo[3,4-d]pyridazines as Anti-Inflammatory Agents

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages: 688–698
Authors:
Osama Ibrahim Abdou Elsabagh
Journal: Arch. Pharm. Chem. Life Sci. 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Volume:
Keywords : Synthesis , Biological Evaluation , Some N-Arylpyrazoles , Pyrazolo[3,4-d]pyridazines    
Abstract:
A series of 3,4-bis-chalcone-N-arylpyrazoles 3a–k was prepared from diacetyl pyrazoles 2a–e. The reaction of 2d and 2e with hydrazine hydrate gave pyrazolo[3,4-d]pyridazine derivatives 4a–b. Furthermore, the reaction of 2a–e with thiosemica
    
     
 
       

Author Related Publications

  • Osama Ibrahim Abdou Elsabagh, "Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors", Taylor & Francis Group, 2022 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis of Some New Benzisothiazolone and Benzenesulfonamide Derivatives of Biological Interest Starting from Saccharin Sodium", 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2013 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity", springer, 2012 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis and pharmacological studies for some new benzotriazole and dibenzodiazepine derivatives as antipsychotic agents", KOREAN CHEMICAL SOC, 2009 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis and antiviral activity of new pyrazole and thiazole derivatives", Elsevier Masson SAS., 2009 More

Department Related Publications

  • Mansour Alsayed Mansour Abokol, "SYNTHESIS OF SOME PYRIMIDO(4,,5,: 4,5) PYRIMIDO(1,6- A) INDOLE OF POTENTIAL ANTIINFLAMMATORY ANTIPYRETIC ACTIVITIES", Zag. J. Pharm. Sci.,Vol 4,No. 1, pp 36 - 42(, 1993 More
  • Mansour Alsayed Mansour Abokol, "REDUCTION OF 2, 3-DICHLOROMALEIC ANHYDRIDE III; ACYLATIVE REDUCTIVE ELIMINATION", Boll. Chim. Farmaceutico – Anno 136 –pp.685-690 n11 Dicembre (, 1997 More
  • Mohammed Alhuseiny Abdelhamid Elsadek , "Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents", www.elsevier.com/locate/bmcl, 2016 More
  • Alsayed Mohamed Mansour Lashen , "Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents", www.elsevier.com/locate/bmcl, 2016 More
  • Noha Ibrahiem Elsayed Mohamed Zidain, "Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents", www.elsevier.com/locate/bmcl, 2016 More
Tweet