Determination of octreotide and assessment of matrix effects in human plasma using ultra high performance liquid chromatography–tandem mass spectrometry

Faculty Pharmacy Year: 2011
Type of Publication: ZU Hosted Pages: 2081– 2088
Authors:
Omnia Ahmed Emam Ismaiel
Journal: Journal of Chromatography B USA Volume:
Keywords : Determination , octreotide , assessment , matrix effects , human plasma    
Abstract:
A selective UHPLC–MS/MS method for determination of the therapeutic peptide octreotide in human plasma was developed and validated. This assay used a UHPLC C18 column with 1.7 m particle size for efficient separation and an ion-exchange
    
     
 
       

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  • Omnia Ahmed Emam Ismaiel, "Monitoring phospholipids for assessment of ion enhancement and ion suppression in ESI and APCI LC/MS/MS for chlorpheniramine in human plasma and the importance of multiple source matrix effect evaluations", USA, 2008 More
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  • Omnia Ahmed Emam Ismaiel, "Development of a Liquid Chromatography-Negative ESI-Tandem Mass Spectrometry Method for Ibuprofen with Minimization of Matrix Effects Associated with Phospholipids", USA, 2008 More

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