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Investigation of endogenous blood plasma phospholipids, cholesterol and glycerides that contribute to matrix effects in bioanalysis by liquid chromatography/mass spectrometry
Faculty
Pharmacy
Year:
2010
Type of Publication:
ZU Hosted
Pages:
3303 - 3316
Authors:
Omnia Ahmed Emam Ismaiel
Staff Zu Site
Abstract In Staff Site
Journal:
Journal of Chromatography B USA
Volume:
Keywords :
Investigation , endogenous blood plasma phospholipids, cholesterol
Abstract:
Matrix effects caused by compounds endogenous to the biological sample are a primary challenge in quantitative LC/MS/MS bioanalysis. Many approaches have been developed to minimize matrix effects such as optimization of sample extraction
Author Related Publications
Omnia Ahmed Emam Ismaiel, "Non-extractive spectrophotometric determination of memantine HCl, clomipramine HCl and fluvoxamine maleate in pure form and in pharmaceutical products by ion-pair complex formation with rose Bengal.", ScienceDirect, 2020
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Omnia Ahmed Emam Ismaiel, "Monitoring phospholipids for assessment of matrix effects in a liquid chromatography–tandem mass spectrometry method for hydrocodone and pseudoephedrine in human plasma", USA, 2007
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Omnia Ahmed Emam Ismaiel, "Monitoring phospholipids for assessment of ion enhancement and ion suppression in ESI and APCI LC/MS/MS for chlorpheniramine in human plasma and the importance of multiple source matrix effect evaluations", USA, 2008
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Omnia Ahmed Emam Ismaiel, "Assessment of matrix effects and determination of niacin in human plasma using liquid–liquid extraction and liquid chromatography–tandem mass spectrometry", USA, 2008
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Omnia Ahmed Emam Ismaiel, "Development of a Liquid Chromatography-Negative ESI-Tandem Mass Spectrometry Method for Ibuprofen with Minimization of Matrix Effects Associated with Phospholipids", USA, 2008
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Department Related Publications
Magda Mohamed Elsayed Elhenawy, "Colorimetric Estimation of Chlorphenoxamine Hydrochloride in the Presence of Anhydrous Caffeine", The Chinese Pharmaceutical journal, 1995
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Omnia Ahmed Emam Ismaiel, "Determination of Glibenclamide and Metformin Hydrochloride in active Pharmaceutical Ingredients and Combined Dosage Form Using a Stability- Indicating HPLC-UV Method", International, 2013
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Hisham Abdelaziz Mohamed Hashime, "Development and validation of rapid stability indicating HPLC-determinations of antiepileptic drugs Phenobarbital in suppositories and Phenytoin in capsules as well as in urine sample"", Taylor and Francis group, 2013
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Rania Adel Sayed Ahmd, "Application of molecular docking approach in a novel eco-friendly impurity profiling HPLC-UV method for the simultaneous estimation of ternary hypoglycemic pharmaceutical mixture", elsevier, 2022
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Wafaa Wafaa Alsayed Hassan Abdelatef Abolabn, "Application of molecular docking approach in a novel eco-friendly impurity profiling HPLC-UV method for the simultaneous estimation of ternary hypoglycemic pharmaceutical mixture", elsevier, 2022
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