Investigation of endogenous blood plasma phospholipids, cholesterol and glycerides that contribute to matrix effects in bioanalysis by liquid chromatography/mass spectrometry

Faculty Pharmacy Year: 2010
Type of Publication: ZU Hosted Pages: 3303 - 3316
Authors:
Omnia Ahmed Emam Ismaiel
Journal: Journal of Chromatography B USA Volume:
Keywords : Investigation , endogenous blood plasma phospholipids, cholesterol    
Abstract:
Matrix effects caused by compounds endogenous to the biological sample are a primary challenge in quantitative LC/MS/MS bioanalysis. Many approaches have been developed to minimize matrix effects such as optimization of sample extraction
    
     
 
       

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