Multiple administration of PEG-coated liposomal oxaliplatin enhances its therapeutic efficacy: a possible mechanism and the potential for clinical application

Faculty Pharmacy Year: 2012
Type of Publication: ZU Hosted Pages: 176-83
Authors:
Amr Selim Ahmed Ali Abu Lila
Journal: International Journal of Pharmaceutics Elsevier Volume: 1-2
Keywords : Multiple administration , PEG-coated liposomal oxaliplatin enhances    
Abstract:
We previously developed a PEG-coated cationic liposome that enabled dual targeting delivery of oxaliplatin (l-OHP) to both tumor endothelial cells and tumor cells in a solid tumor. The targeted liposomal l-OHP formulation consequently elici
    
     
 
       

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