The accelerated blood clearance (ABC) phenomenon: clinical challenge and approaches to manage

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages: 38-47
Authors:
Amr Selim Ahmed Ali Abu Lila
Journal: Journal of Controlled Release Elsevier Volume: 1
Keywords : , accelerated blood clearance (ABC) phenomenon: clinical    
Abstract:
Despite the clinical introduction of an increasing number of polyethylene glycol (PEG)-conjugated substances, PEG has been named as the cause of an unexpected immunogenic response known as the "accelerated blood clearance (ABC) phenomenon."
    
     
 
       

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