Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Bioorganic & Medicinal Chemistry Letters ELSEVIER Volume:
Keywords : Design, synthesis , , vitro anticancer evaluation , 4,6-diamino-1,3,5-triazine-2-carbohydrazides    
Abstract:
Series of substituted 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides have been synthesised, based on molecular modelling of candidate structures related to the previously reported Rad6B-inhibitory diamino-triazinylmethyl ben
   
     
 
       

Author Related Publications

  • Mansour Alsayed Mansour Abokol, "Synthesis of certain Arylalkanoic Acid Derivatives of pharmacutical Interest", لايوجد, 1900 More
  • Mansour Alsayed Mansour Abokol, "SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN- 4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS.", International, 2013 More
  • Mansour Alsayed Mansour Abokol, "Synthesis and biological screening of new derivatives of 2,3-dihydro quinazolin-4(1H)-one and benzotriazepin- 5(2H)-one for central nervous system activity", International, 2014 More
  • Mansour Alsayed Mansour Abokol, "DESIGN AND SYNTHESIS OF N4, N9- DISUBSTITUTED SPERMINES FOR NON-VIRAL SIRNA DELIVERY – STRUCTURE – ACTIVITY RELATIONSHIP STUDIES OF SIFECTION EFFICIENCY VERSUS TOXICITY", Pharmaceutical Research, Vol. 26, No. 2, February (2009), 2009 More
  • Mansour Alsayed Mansour Abokol, "DESIGN AND SYNTHESIS AND IN VITRO ANTICANCER EVALUATION OF 4,6-DIAMINO 1,3,5-TRIAZINE-2-CARBOHYDRAZIDES AND CARBOXAMIDES", Med. Chem. Lett. 23, 2013 More

Department Related Publications

  • Mansour Alsayed Mansour Abokol, "SYNTHESIS AND PRELIMINARY TESTING OF SOME ANTHRANILIC ACID DERIVATIVES AS ANTIIFLAMMATORY, ANALGESIC AND ANTIPYRETIC AGENTS", Zag. J. Pharm. Sci., Vol. 2 No. 1. Pp 140-149 June, 1993 More
  • Ahmed Gamal Mohamed Abdallah Eissa, "Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation", MDPI, 2023 More
  • Samar Saied Mahmoud Mohamed Elbaramawy, "Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation", MDPI, 2023 More
  • Nada Abdasattar mohamed Noureddine, "Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation", MDPI, 2023 More
  • Samar Saied Mahmoud Mohamed Elbaramawy, "Developing a highly validated and sensitive HPLC method for simultaneous estimation of cefotaxime and paracetamol in pure and pharmaceutical preparations", GrowingScience, 2023 More
Tweet