Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages:
Authors:
Mansour Alsayed Mansour Abokol
Journal: Bioorganic & Medicinal Chemistry Letters ELSEVIER Volume:
Keywords : Design, synthesis , , vitro anticancer evaluation , 4,6-diamino-1,3,5-triazine-2-carbohydrazides    
Abstract:
Series of substituted 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides have been synthesised, based on molecular modelling of candidate structures related to the previously reported Rad6B-inhibitory diamino-triazinylmethyl ben
    
     
 
       

Author Related Publications

  • Mansour Alsayed Mansour Abokol, "Synthesis of certain Arylalkanoic Acid Derivatives of pharmacutical Interest", لايوجد, 1900 More
  • Mansour Alsayed Mansour Abokol, "SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN- 4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS.", International, 2013 More
  • Mansour Alsayed Mansour Abokol, "Synthesis and biological screening of new derivatives of 2,3-dihydro quinazolin-4(1H)-one and benzotriazepin- 5(2H)-one for central nervous system activity", International, 2014 More
  • Mansour Alsayed Mansour Abokol, "DESIGN AND SYNTHESIS OF N4, N9- DISUBSTITUTED SPERMINES FOR NON-VIRAL SIRNA DELIVERY – STRUCTURE – ACTIVITY RELATIONSHIP STUDIES OF SIFECTION EFFICIENCY VERSUS TOXICITY", Pharmaceutical Research, Vol. 26, No. 2, February (2009), 2009 More
  • Mansour Alsayed Mansour Abokol, "DESIGN AND SYNTHESIS AND IN VITRO ANTICANCER EVALUATION OF 4,6-DIAMINO 1,3,5-TRIAZINE-2-CARBOHYDRAZIDES AND CARBOXAMIDES", Med. Chem. Lett. 23, 2013 More

Department Related Publications

  • Mansour Alsayed Mansour Abokol, "SPECTROPHOTOMETRIC DETERMINATION OF KETOPROFEN IN PHARMACEUTICAL PREPARATIONS BY MEANS OF CHARGE TRANSFER COMPLEXES", Talnta. Vol. 40. No. 4 pp. 585-588, 1993 More
  • Mansour Alsayed Mansour Abokol, "REACTION OF 2, 3- DICHLOROMALEIC ANHYDRIDE I: NITROSATIVE REDUCTIVE ELIMINATION; SYNTHESIS OF N-(2,6-DIMETHYLPHENYL)-2-(N-NITROSO-N-SUBSTITUTED)AMINO- SUCCINIMIDES", Chim. Farmaceutico – Anno 135 –pp.429-433 n. 7 Luglio/Agosto, 1996 More
  • Mansour Alsayed Mansour Abokol, "UTILITY OF DICHLOROMALEIMIDE DERIVATIVE AS CHROMOGENIC REAGENT FOR THE SPECTROPHOTOMETRIC DETERMINATION OF CERTAIN FLUOROQUINOLOINES AND RELATED COMPOUNDS", Mansour E.Abou Kull. Zagazig J.Pharm.sci., Dec.(1999) Vol.8 No.2, p13-17, 1999 More
  • Mahmoud Mohamed Mohamed Sebaee, "Different techniques for overlapped UV spectra resolution of some co-administered drugs with paracetamol in their combined pharmaceutical dosage forms", Elsevier, 2019 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Eco-friendly novel deconvoluted synchronous spectrofluorimetric approach for the determination of favipiravir, levodropropizine and moxifloxacin hydrochloride as an effective therapeutic combination for COVID-19; application in laboratory prepared mixtures and spiked human plasma", Elsevier, 2023 More
Tweet