Novel Inhibitors of Rad6 Ubiquitin Conjugating Enzyme: Design, Synthesis, Identification, and Functional Characterization

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Molecular Cancer Therapeutics AACR publications Volume:
Keywords : Novel Inhibitors , Rad6 Ubiquitin Conjugating Enzyme:    
Abstract:
Protein ubiquitination is important for cell signaling, DNA repair, and proteasomal degradation, and it is not surprising that alterations in ubiquitination occur frequently in cancer. Ubiquitin-conjugating enzymes (E2) mediate ubiquitinati
   
     
 
       

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