Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages:
Authors:
Hend Kather Abdelhakem Elhamalawy
Journal: Medicinal chemistry Research springer link Volume:
Keywords : Synthesis , , benzotriazepin-5(2H)-one derivatives , expected antipsychotic activity    
Abstract:
A new series of 3,4-dihydro-1H-benzo[e][1,2,4] triazepin-5(2H)-one derivatives were synthesized by cyclocondensation of benzohydrazides (II, IX), derived from the reaction ofN-methyl-isatoic anhydride with phenyl hydrazine and isonicoti
    
     
 
       

Author Related Publications

  • Hend Kather Abdelhakem Elhamalawy, "Preclinical evaluation of Rad6 inhibition to overcome platinum resistance in ovarian cancer", AACR, 2016 More
  • Hend Kather Abdelhakem Elhamalawy, "Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides", ELSEVIER, 2013 More
  • Hend Kather Abdelhakem Elhamalawy, "Synthesis of New 2,3-Dihydroquinazolin-4(1H)-one Derivatives for Analgesic and Anti-inflammatory Evaluation", WILEY interscience, 2010 More
  • Hend Kather Abdelhakem Elhamalawy, "Novel Inhibitors of Rad6 Ubiquitin Conjugating Enzyme: Design, Synthesis, Identification, and Functional Characterization", AACR publications, 2013 More
  • Hend Kather Abdelhakem Elhamalawy, "RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance", Springer Nature., 2017 More

Department Related Publications

  • Mansour Alsayed Mansour Abokol, "SYNTHESIS OF SOME PYRIMIDO(4,,5,: 4,5) PYRIMIDO(1,6- A) INDOLE OF POTENTIAL ANTIINFLAMMATORY ANTIPYRETIC ACTIVITIES", Zag. J. Pharm. Sci.,Vol 4,No. 1, pp 36 - 42(, 1993 More
  • Mansour Alsayed Mansour Abokol, "REDUCTION OF 2, 3-DICHLOROMALEIC ANHYDRIDE III; ACYLATIVE REDUCTIVE ELIMINATION", Boll. Chim. Farmaceutico – Anno 136 –pp.685-690 n11 Dicembre (, 1997 More
  • Mohammed Alhuseiny Abdelhamid Elsadek , "Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents", www.elsevier.com/locate/bmcl, 2016 More
  • Alsayed Mohamed Mansour Lashen , "Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents", www.elsevier.com/locate/bmcl, 2016 More
  • Noha Ibrahiem Elsayed Mohamed Zidain, "Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents", www.elsevier.com/locate/bmcl, 2016 More
Tweet