Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Bioorganic & Medicinal Chemistry Letters ELSEVIER Volume:
Keywords : Design, synthesis , , vitro anticancer evaluation , 4,6-diamino-1,3,5-triazine-2-carbohydrazides    
Abstract:
Series of substituted 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides have been synthesised, based on molecular modelling of candidate structures related to the previously reported Rad6B-inhibitory diamino-triazinylmethyl ben
   
     
 
       

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